Bis-hydrophilic and Functional Triblock Terpolymers Based on Polyethers: Synthesis and Self-Assembly in Solution

Barthel, Markus J.; Babiuch, Krzysztof; Rudolph, Tobias; J\", ; urgen Vitz, ; Höppener, Stephanie; Gottschaldt, Michael; Hager, Martin D.; Schacher, Felix H.; Schubert, Ulrich S.

Abstract:

A well-defined triblock terpolymer, poly(ethylene glycol)-block-poly(allyl glycidyl ether)-block-poly(tert-butyl glycidyl ether) (PEG-b-PAGE-b-Pt-BGE), with a narrow molar mass distribution has been synthesized by sequential living anionic ring-opening polymerization. Afterward, the PAGE block was modified via thiol-ene chemistry and different sugar moieties or cysteine as a model compound for peptides could be covalently attached to the polymer backbone. The solution self-assembly of the obtained bis-hydrophilic triblock terpolymers in aqueous media has been studied in detail by turbidimetry, dynamic light scattering, and transmission electron microscopy (TEM and cryo-TEM).

Year:

2012

Type of Publication:

Article

Keywords:

ABC triblock terpolymers; anionic ring-opening polymerization; anionic polymerization; living polymerization; polyethylene glycol; polyethers; self-assembly; thiol-ene chemistry

Journal:

Journal of Polymer Science: Part A: Polymer Chemistry

Volume:

50

Pages:

2914 - 2923