Antibacterial effect of silver (I) carbohydrate complexes on oral pathogenic key species in vitro

Reise, Markus; Gottschaldt, Michael; Matz, Carina; Völpel, Andrea; Jandt, Klaus D.; Schubert, Ulrich S.; Sigusch, Bernd W.

Abstract:

It was the aim of this study to evaluate the antibacterial impact of two silver(I) carbohydrate complexes with tripodal thioglycosides, namely tris[2-(β-D-thio-glucopyranosyl)ethyl]-amine-silver(I)-nitrate (3) and tris[2-(α-D-thio-manno-pyranosyl)ethyl]-amine-silver(I)-nitrate (4), on five oral pathogenic bacterial strains. Furthermore, cytocompatibility was tested using human gingival fibroblasts (HGF).

Research areas:

• Biotechnology

Year:

2016

Type of Publication:

Article

Journal:

BMC Oral Health

Volume:

16

Number:

42

Pages:

1 - 9

DOI:

10.1186/s12903-016-0201-4