Synthesis of d-fructose conjugated ligands via C6 and C1 and their corresponding [Ru(bpy)2(L)]Cl2 complexes

Pröhl, Michael; Moser, Pascal D.; Czaplewska, Justyna; Hoffmann, Patrick; Buś, Tanja; Träger, Anja; Goerls, Helmar; Schubert, Ulrich S.; Gottschaldt, Michael

Abstract:

A pyridyl triazole (pyta) modified sucrose ligand was prepared in a seven step synthesis using d-glucose as the protection group for d-fructose and starting from commercially available sucrose. After complexation with Ru(bpy)2Cl2 precursor, the sucrose-conjugated Ru complex of the general formula [Ru(bpy)2(L)]Cl2 was formed. Acidic cleavage of the d-glucose unit led to the first d-fructose conjugated metal complex viad-fructose C6 in literature. Additionally, pyta-modified d-fructose via C1 and the corresponding Ru complex were synthesized. All compounds were analyzed by Rf values, specific rotation, NMR, IR, UV/Vis and fluorescence spectroscopy, mass spectrometry and elemental analysis.

Research areas:

• Supramolecular Chemistry

Year:

2017

Type of Publication:

Article

Volume:

446 - 447

Pages:

19 - 27

ISSN:

Carb-ohyd

DOI:

10.1016/j.carres.2017.04.020