Synthesis, Complete Characterization, and Enantioselective Electrokinetic Separation of Functionalized Ruthenium Complex Enantiomers
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Holder, Elisabeth; Trapp, Oliver; Trapp, Gabriele; Marin, Veronica; Hoogenboom, Richard; Schubert, Ulrich S.
- Abstract:
- Electrokinetic chromatography was employed to separate the enantiomers
of two novel functionalized ruthenium(II) complexes with different polypyridyl
coordination spheres. The use of anionic carboxymethyl-b-cyclodextrin as chiral mobile
phase additive resulted in maximum efficiency and resolution for the enantiomer
separation of both transition metal complexes. The syntheses of the [4-(3-hydroxypropyl)-
4'-methyl-2,2'-bipyridine]-bis(2,2'-bipyridine)ruthenium(II)-bis(tetrafluoroborate) and [4-
(3-hydroxypropyl)-4'-methyl-2,2'-bipyridine]-bis(4,4'-dimethyl-2,2'-bipyridine)ruthenium
(II)-bis(tetrafluoroborate) complexes and their complete characterization by means of
two-dimensional 1H and 13C{1H} NMR techniques (1H–1H COSY and 1H–13C HMQC)
as well as elemental analyses and MALDI-TOFMS are described in detail. The functionalized
complexes can be used as building blocks for further reactions with polymers,
biopolymers, surfaces and nanoparticles.
- Year:
- 2004
- Type of Publication:
- Article
- Journal:
- Chirality
- Volume:
- 16
- Pages:
- 363 - 368