Fast, ligand- and solvent-free copper-catalyzed click reactions in a ball mill
-
Thorwirth, Rico; Stolle, Achim; Ondruschka, Bernd; Wild, Andreas; Schubert, Ulrich S.
- Abstract:
- A new, ligand- and solvent-free method for the Huisgen
1,3-dipolar cycloaddition (click reaction) was developed using
a planetary ball mill. Besides various alkynes and azides, a
propargyl functionalized polymer was converted by mill clicking.
Moreover, it was possible to carry out a click polymerization in
a ball mill.
- Year:
- 2011
- Type of Publication:
- Article
- Journal:
- Chemical Communications
- Volume:
- 47
- Pages:
- 4370 - 4372