Analysis of Different Synthetic Homopolymers by the use of a New Calculating Software for Tandem MS Spectra

Baumgärtel, Anja; Scheubert, Kerstin; Pietsch, Bernhard; Kempe, Kristian; Crecelius, Anna; Böcker, Sebastian; Schubert, Ulrich S.

Abstract:

The manual interpretation of tandem mass spectra of synthetic polymers is very time‐consuming. Therefore, a new software tool was developed to accelerate the interpretation of spectra obtained without requiring any further knowledge about the polymer class or the fragmentation behavior under high‐energy collision‐induced dissociation (CID) conditions. The software only requires an alphabetical list of elements and a peak list of the measured substance as an xml file for the evaluation of the chosen mass spectrum. Tandem mass spectra of different homopolymers, like poly(2‐oxazoline)s, poly(ethylene glycol) and poly(styrene), were interpreted by the new software tool. This contribution describes a fast and automated software tool for the rapid analysis of homopolymers.

Year:

2011

Type of Publication:

Article

Journal:

Rapid Communications in Mass Spectrometry

Volume:

25

Pages:

1765 - 1778