Abundance correction for mass discrimination effects in polymer mass spectra
-
Engler, Martin S.; Crotty, Sarah; Barthel, Markus J.; Pietsch, Christian; Schubert, Ulrich S.; Böcker, Sebastian
- Abstract:
- Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) is frequently used to analyze homo- and copolymers, i.e. for computing copolymer fingerprints. However, the oligomer abundances are influenced by mass discrimination, i.e. mass- and composition-dependent ionization. We have developed a computational method to correct the abundance bias caused by the mass discrimination.
- Research areas:
- Year:
- 2016
- Type of Publication:
- Article
- Journal:
- Rapid Communications in Mass Spectrometry
- Volume:
- 30
- Pages:
- 1233 - 1241
- DOI:
- 10.1002/rcm.7553