A polyesteramide library from dicarboxylic acids and 2,2′-bis(2-oxazoline): synthesis, characterization, nanoparticle formulation and molecular dynamics simulations

Muljajew, Irina; Erlebach, Andreas; Weber, Christine; Buchheim, Johannes R.; Sierka, Marek; Schubert, Ulrich S.
Abstract:
The step growth polyaddition of a variety of dicarboxylic acids and 2,2′-bis(2-oxazoline) enabled access to a library of polyesteramides (PEA) with different linker lengths or bulkiness. PEA with alkylene spacers represented semicrystalline materials due to hydrogen bond formation between the oxamide moieties, as is evident from dynamic scanning calorimetry and wide-angle X-ray scattering (145 °C hough Hildebrand parameters alone provided less accurate solubility predictions of the PEAs in acetone and THF, the Flory–Huggins parameters χPS revealed pronounced changes of intermolecular interactions with variation of the polymer structure, clearly demonstrating a tunable hydrophobicity of the synthesized PEAs.
Year:
2020
Type of Publication:
Article
Journal:
Polymer Chemistry
Volume:
11
Pages:
112 - 124